种植体周围龈沟液中酶水平的研究

A one year study on enzyme level in gingival crevicular fluid around osseointegrated dental implants

目的 初步探讨种植体修复后第 1年内龈沟液 (gingivalcrevicularfluid ,GCF)量及其中的天冬氨酸转氨酶 (aspartateaminotransferase ,AST)和碱性磷酸酶 (alkalinephosphatase ,ALP)水平的变化 ,及其与种植体周围组织炎症及骨丧失的关系。方法 以基台连接术后 1～ 1 5个月为基线 ,修复后 3、6、12个月时分别对 12例患者 2 6个Branemark种植体的 5 2个位点进行检测。结果 GCF量、GCF AST、GCF ALP水平在修复后第 1年内呈先升高后下降的趋势。各时期种植体周围粘膜炎组的GCF量、GCF AST、GCF ALP水平普遍高于健康组 ,且有随炎症程度加重而升高的趋势。有骨丧失位点的GCF量、GCF AST、GCF ALP水平均明显高于无骨丧失位点。结论 GCF量、GCF AST、GCF

Objective To investigate the changes of gingival crevicular fluid(GCF)volume, aspartate aminotransferase (AST)and alkaline phosphatase(ALP)levels in GCF around dental implants during the first year after rehabilitation And to explore the relationships between these changes and peri implant inflammation as well as bone loss Methods 26 Branemark implants in 12 adults were included in this study Examinations were carried out in a total of 52 sites in preinsertion period and 3, 6, 12 months following rehabilitation Results GCF volume, GCF AST, GCF ALP were firstly increased and then fallen during the first year after rehabilitation GCF volume, GCF AST, GCF ALP in sites with peri implant mucositis were higher than those in health sites, and were increased with the severity of peri implant mucositis GCF volume, GCF AST, GCF ALP in sites with bone loss were significantly higher than those without bone loss Conclusion GCF volume, GCF AST, GCF ALP could reflect peri implant inflammation and bone changes to some degree