中心静脉导管相关血流感染耐药菌分析

Central Venous Catheter-related Bloodstream Infections Resistant Analysis

目的:分析ICU内中心静脉导管相关性血流感染(CRBSI)病原菌的分布特点及其耐药性,加强监控,为临床预防诊疗提供依据,以指导临床合理用药。方法:回顾性分析2009年1月-2010年12月ICU内CRBSI患者的病原菌分布和药物敏感试验资料。结果:多数细菌对不同抗菌药物有不同的耐药,未检出对万古霉素耐药的革兰氏阳性球菌。结论:导管相关性感染病原菌种属多样化,耐药率高,加强ICU耐药性监测,合理应用抗生素,并落实有效地持续改进措施,是预防中心静脉导管相关血流感染耐药菌的重要措施。

Objective：To analyze distribution characteristics and drug resistance of pathogenic bacteria of central ve nous catheter-related bloodstream infection in ICU （CRBSI）, and provide basis for clinical prevention and treatment, and to guide clinical rational drug use. Methods： The distribution of pathogenic bacteria and drug sensitivity test were retrospectively analyzed in January 2009 to July 2010 data of patients with ICU in CRBSL Results：The maiority of bac- teria have different resistance to different antibiotics, not detected gram-positive cocci resistant to vaneomyein. C_~~lu- sion：Pathogenic bacteria of diversification, high rates of resistance, paid attention to in operation {or clinical aseptic, strengthen management, are important measures to prevent drug-resistant bacteria of central venous catheter related bloodstream infection.