预防琥珀胆碱的肌震颤的对策

Prevention of tetanic associated with succinglcholine

目的 :采取一些对策 ,预防琥珀胆碱的肌震颤。方法 :30例手术病人随机分成三组 : 组麻醉诱导用 2 .5%硫喷妥钠 5mg/ kg,静脉快速推注琥珀胆碱 1mg/ kg。 、 组麻醉诱导用芬太尼、依托咪酯 ,琥珀胆碱的剂量 组为 1mg/ kg、 组为 0 .8mg/ kg。结果 : 组肌震颤程度最低 ,与 组有非常显著的差异 (P<0 .0 1)。结论 :麻醉诱导选择芬太尼、依托咪酯 ,琥珀胆碱剂量为 0 .8mg/ kg,可基本预防琥珀胆碱的肌震颤。

Objective:[WT5BZ][ST5BZ]To prevent tetanic associated with succinylcholine.[WT5HZ]Methods:[WT5BZ]30 cases of operative patients were divided into 3 groups in radom:Group 1:anesthesia by 2.5% thiopentol(5 mg/kg),Group 2 and 3 by fentangl,etomidate,The dose of succinylcholine is 1 mg/kg in group l or 2, 0.8mg/kg in group 3.[WT5HZ]Results:[WT5BZ]Group 3 showed the lowest ratio of tetanic compared with group 1 (P<0.01).[WT5HZ]Conclusions:[WT5BZ]Tetanic during induclion of anesthesia associated with succinylcholine can be prevented by fentanyl,etomidate and succinylchoine (0.8mg/kg). [WT5HZ]