端粒酶在慢性宫颈炎和宫颈癌中的表达及意义

Telomerase in cervical intraepithelial neoplasia of change and the expression of cervical cancer and significance

目的探讨端粒酶与宫颈炎和宫颈癌变发生的相关性。方法对97例慢性宫颈炎、31例宫颈浸润性鳞癌(ISCC)标本采用免疫组化S-P法检测端粒酶活性。结果端粒酶在宫颈慢性炎中无表达,在ISCC中阳性率为82.47%,呈高表达。结论端粒酶活性的表达与宫颈炎、宫颈癌的发生密切相关。

Objective： To explore the telomerase activity and cervical cancer is to do something. Methods： 97 cases of chronic cervicitis, 31 cases of cervical infiltrating squamous cell carcinoma （ISCC） specimens by immunohistochemical S -P method detection of telomerase activity. Results： Telomerase in cervical chronic inflammatory in no expression, ISCC in the positive rate was 82. 47%, into high expression. Conclusion ： The expression of the activity of telomerase and cervical cancer closely related to the occurrence of.