摘要
Polyelectrolyte PTPEPyH,containing tetraphenylethene(TPE)and pyridinium,was synthesized.Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin.The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings.The polyelectrolyte PTPEPyH,compared with ChS and HA,also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.
Polyelectrolyte PTPEPyH, containing tetraphenylethene （TPE） and pyridinium, was synthesized. Its optical properties were investigated with spectroscopies and the results showed that there were two emission-enhanced stages in the interaction between positive-charged PTPEPyH and negative-charged biomacromolecule heparin. The mechanism was very different due to the reduced non-radiative energy loss and the change of surroundings. The polyelectrolyte PTPEPyH, compared with ChS and HA, also showed high selectivity for heparin in the buffer solution and could be used as a potential bio-probe for heparin quantification in the clinical full range.
出处
《中国科学：化学》
CAS
CSCD
北大核心
2013年第9期1213-1213,共1页
SCIENTIA SINICA Chimica
关键词
聚电解质
肝素
检测范围
荧光探针
传感
生物大分子
硫酸软骨素
光学特性
aggregation-induced emission enhancement （AIEE）, tetraphenylethene （TPE）, heparin quantification, pyridinium, biosensor
