中西医结合治疗慢性萎缩性胃炎恢复期成本效果分析

The economic analysis of integrated traditional Chinese and western medicine in treatment of chronic atrophic gastritis

目的探讨3种方案治疗慢性萎缩性胃炎(CAG)的经济效果。方法将171例确诊为CAG的患者按就诊顺序采用随机数字表法分为A、B、C组,分别服用泮托拉唑肠溶胶囊+克拉霉素+阿莫西林胶囊(A组)、法莫替丁片+克拉霉素+萎胃宁(B组)、法莫替丁片+克拉霉素+硫糖铝(C组)进行治疗,疗程4周,观察疗效,并进行成本-效果分析。结果 A、B、C组总有效率分别为84.06%、83.60%、56.10%,成本-效果比分别为5.21、4.13、4.02,敏感度分析结果为B组最优。结论对CAG B组治疗方案具有最佳的性价比。

Objective To investigate the cost-effectiveness of three therapeutic schemes on chronic atrophic gastritis CAG. Methods According to the registration order and random digits table, a total of 171 patients diagnosed as CAG were assigned into Group A treated with pantoprazole, clarithromycin and amoxycillin, Group B treated with famotidine, clarithromycin and weiweining and Group C treated with famotidine, clarithromycin and sucralfate for four weeks. Their cost-effectiveness was compared. Results In Group A, B and C, the total effective rates were 84.06% , 83.60% and 56.10% , and the cost-effectiveness was 5.21,4.13 and 4.02, respectively. The sensitivity analysis showed that Group B was more appropriate. Conclusion The herapeutic scheme with famotidine, clarithromycin and weiweining is preferable in terms of cost-effectiveness.