摘要
目的:探讨匹伐他汀治疗心力衰竭(HF)合并阵发性心房颤动(AF)的临床疗效。方法:HF合并阵发性AF的患者220例,随机分为治疗组(常规治疗+匹伐他汀组,110例)及对照组(常规治疗组,110例)。治疗并随访1年,比较治疗前后左室射血分数(LVEF)、C-反应蛋白(CRP)和脑钠肽(BNP)水平变化。结果:治疗半年后,治疗组LVEF明显高于对照组(P<0.05);治疗组CRP、BNP水平明显低于治疗组(P<0.05)。结论:匹伐他汀能有效减少AF的复发,改善心功能,降低BNP和CRP。
Objective: To explore the pitavastatin treatment of heart failure(HF) clinical efficacy of paroxysmal atrial fibrillation(AF).Methods: HF complicated by paroxysmal AF of 220 patients were randomly divided into treatment group(conventional treatment + pitavastatin group,110 cases) and control group(conventional treatment group,110 patients).Treatment and follow-up of 1 year,before and after treatment,left ventricular ejection fraction(LVEF),C-reactive protein(CRP) and brain natriuretic peptide(BNP) levels.Results: After six months of treatment,the treatment group LVEF was significantly higher(P&lt;0.05);treatment group CRP,BNP levels were significantly lower in the treatment group(P&lt;0.05).Conclusions: Pitavastatin statins can effectively reduce the recurrence of AF,improve HF and reduce the BNP and CRP.
出处
《中国医药导刊》
2013年第7期1204-1204,1206,共2页
Chinese Journal of Medicinal Guide
关键词
匹伐他汀
心力衰竭
阵发性心房颤动
Pitavastatin
Heart failure
Paroxysmal atrial fibrillation