摘要
XIAP(X链锁凋亡抑制蛋白,X-linked inhibitor-of-apoptosis protein)是凋亡抑制蛋白(inhibitor of apoptosis protein,IAP)家族中最有效力的caspase抑制物,具有抑制细胞凋亡,参与肿瘤的发生、发展。本研究就XIAP在肿瘤中的作用机制、表达及治疗情况做一综述,有望为肿瘤的诊断及治疗提供一个新方法。
XIAP （X-linked inhibitor-of-apoptosis protein） is inhibitor of apoptosis protein （IAP） family to most effective caspase inhibit, with inhibiting cell apoptosis, participate in the occurrence and development of tumor. In this paper, the mechanism, expression and treatment of XIAP were reviewed, expecting to provide a new method in diagnosis and treatment of tumor.
出处
《疾病监测与控制》
2013年第9期541-543,共3页
Journal of Diseases Monitor and Control
关键词
X链锁凋亡抑制蛋白
细胞凋亡
肿瘤
X-linked inhibitor-of-apoptosis protein
Apoptosis
Tumor
