中国甲状腺癌发病趋势分析

Epidemiological Study on Thyroid Cancer in China

[目的]分析中国甲状腺癌发病变化水平及流行特点,为制定中国甲状腺癌防治策略提供参考依据。[方法]甲状腺癌发病数据来源于1988～2009年《中国肿瘤登记年报》及《部分登记点肿瘤登记年报》。计算粗发病率,0～64岁累积率,采用1982年全国人口构成计算中标率;变化百分比计算总体变化趋势;年度平均变化百分比计算各年平均变化趋势。[结果]中国登记地区甲状腺癌粗发病率由1988年的1.78/10万升高至2009年的6.56/10万,变化百分比(PC%)达236.72%,年度变化百分比(APC%)为5.92%。女性发病率为10.09/10万,高于男性的3.11/10万(χ2=369.11,P<0.001);城市发病率为8.25/10万,高于农村的3.09/10万(χ2=727.848,P<0.001)。[结论]1988～2009年中国甲状腺癌发病率呈上升趋势,应加强对重点人群的监测。

[Purpose] To investigate the incidence and epidemiological features of thyroid cancer in China in order to provide basic information for making cancer control strategy. [Methods] The cancer incidence data from Chinese Cancer Registry Annual Report and other cancer registry database that published were retrieved.Crude incidence rate,0～64 cumulative rate and age-standardized were calculated.Percent change and annual percent change was evaluated for temporal change. [Results] The thyroid cancer incidence in cancer registration areas was increased from 1.78/10 5 in 1988 to 6.56/10 5 in 2009 with PC% of 236.72% and APC% of 5.92%. Female incidence was 10.09/10 5 ,which was higher than that in male（3.11/10 5 ）（χ2 =369.11,P0.001）;incidence in urban was 8.25/10 5 ,which was higher than that in rural（3.09/10 5 ）（χ2 =727.848,P0.001）.[Conclusions] Incidence of thyroid cancer is increasing sharply from 1988 to 2009 in China,prevention for high-risk group of thyroid cancer should be strengthened.