摘要
目的 观察复合生长因子治疗创伤性溃疡的临床效果。方法 将 17例正颌外科患者术后的双侧创伤性口角溃疡随机分成用药侧和对照侧。用药侧创面涂擦复合生长因子 ,对照侧涂擦生理盐水。应用开放型质反应双向序贯实验法进行疗效评价。结果 当实验观察到第 17例时 ,结果显示复合生长因子促创面愈合作用优于生理盐水。所有创面都能愈合 ,用药创面与对照创面愈合的差异主要在于愈合时间 ,用药创面愈合均在 1周之内 ,而对照创面 1周内愈合的仅 3例 ,其余为 10～ 12d。结论 局部应用复合生长因子是加速创伤性溃疡愈合的有效措施。
Objective To observe clinical effects of poly growth factor on traumatic ulcer of mouth angle after orthognathic surgery by sequential analysis.Methods Patient's wounds were randomly divided into two groups: Polygrowth factor experimental group and normal saline control group. Wound healing conditions were obser-ved by sequential analysis. Results The result of the observation of the 17 cases indicated that the polygrowth factor better than saline in wound healing. Although all wounds heale,the main defference between the two groups lay in the time of healing, generally wound healing time in polygrowth factor group was shorter (all wounds healed within 1 week ) and in normal saline group longer(3 cases healed within 1 week, rest healed within 10～12 days). Conclusion It suggests that local application of polygrowth factor is an effective method to improve the condition of traumatic ulcer healing.
