摘要
骨髓造血完全依赖骨髓微环境的支持和调控 ,早期和近期的观察均提出了辐射对骨髓造血微环境基质细胞的远期影响 ,并发现在某些实验条件下 ,辐射后基质细胞的集落刺激能力上升 ,生长因子 (如 GM- GSF)和粘附分子 (如 VCAM- 1)
Hemoto poiesis completely depends on the regulation of the microenvironment. It has been indicated in the early and recent study the long term effects of radiation on bone marrow microenvironment. It has been found in some experiments that after radiation the colony stimulating activity, the expression of growth factor (GM CSF) and adhesion molecule(VCAM 1) of the stroma cells was elevated.
出处
《国外医学(放射医学核医学分册)》
2000年第4期183-185,共3页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词
辐射
骨髓基质细胞
生长因子
粘附分子
微环挠
irradiation
bone marrow stroma cell
growth factor
adhesion molecule