中西医结合治疗消化道肿瘤135例疗效观察

Therapeutic Effect on Malignant Tumors of Digestive Tract by Combined Treatment,Analysis of 135 Cases

目的 :对消化道肿瘤采用手术、术中化疗、术后介入化疗、中药辅助治疗 ,观察近、远期治疗效果。 方法 :对 135例消化道肿瘤采用手术切除原发病灶 ,术后动脉区域化疗、服用中药 ,并与单纯手术治疗组 12 5例进行疗效对照研究。 结果 :综合治疗组完全缓解 (CR) 4 9例 ,部分缓解 (PR) 6 2例 ,显效率为 82 2 % ,5年存活率为 74 1% ,明显优于单纯手术治疗组 (CR +PR为 32 8% ,P <0 .0 5 )。 结论 :采用手术切除原发病灶、术中化疗、术后区域性介入化疗、辅助中药治疗胃肠道肿瘤有较好的治疗效果 ,特别是对预防术后复发 ,提高病人生存质量有一定的临床价值。

Objective:To observe the short and long term follow up results on treatment of malignant tumors of the digestive tract by excision,intraoperative chemotherapy postoperative interventional chemotherapy and accessory treatment with traditional Chinese herbal medicine Methods:In 135 cases of malignant tumors of the digestive tract methods of excision on primary focus,postoperative interventionl chemotherapy with combined herbal medicine were used.During the same period,125 cases of malignant tumors of the digestive tract were treated by excision only,and cross check analysis of the two group were made.Results:In the combined group,complete response(CR)was found in 49 cases and partial response(PR)in 62 cases,the effective rate being 82.2% and the 5 year survival rate was 74.1%,obviously higher than the excision group(of CR+PR=32.8%,P<0.05).Conclusion:The combined treatment shows a better therapeutic effect,and also effect on prevention of postoperative recurrance with improvement of the patients living quality standard.