TUBEX技术在伤寒、副伤寒诊断中的应用概况

伤寒和副伤寒是古老的疾病,传染性强、病程长、易复发、并发症多、疾病负担较重,在一些地区常以暴发形式发生,往往表现出不明原因发热,在发热症状监测中需要排除该病。因此,在突发公共卫生事件的处理中,需要快速、灵敏的方法进行确诊和鉴别患者是否罹患该病。TUBEX是一种快速的半定量血清检测方法,所需材料简单,对环境要求不高,易于操作,值得临床推广应用。

Typhoid and paratyphoid fever has been a disease affected human for thousands of years, which is highly contagious, long-course, frequently relapsing and has complex complication and high disease burden. In some areas, typhoid and paratyphoid fever frequently causes outbreaks, and is commonly characterized with fever of unknown reason. It needs to be excluded when conducting fever syndromic surveillance. Therefore, rapid and sensitive assay is needed to make diagnosis and differential diagnosis of the disease. TUBEX is a rapid semiquantitative serology test for typhoid and paratyphoid fever. The test requires simple materials and environmental conditions and is easily operational.