2型糖尿病合并非酒精性脂肪肝与胰岛素抵抗及心血管病变发生的关系

目的针对2型糖尿病合并酒精性脂肪肝的患者在临床治疗上的相关因素,探讨与胰岛素抵抗以及心血管病变之间的关系。方法回顾性分析2010-2012年到本院进行治疗的2型糖尿病患者100例。将这100例患者根据病情分为两组,合并非酒精性脂肪肝为实验组,不合并酒精性脂肪肝为对照组,将两组患者的资料进行统一的整合,包括一般资料、血脂水平、胰岛功能等,然后对比实验组和对照组之间的差别。结果实验组患者体内丙氨酸氨基转移酶以及谷氨酰转肽酶的含量要高,血清三酰甘油的含量也较高,相关胰岛素水平也升高,这样就可以明显看出患者脑血管病变以及代谢方面的症状等疾病的发生率明显高于对照组,在实际比较的过程中,具有统计学差异。结论 2型糖尿病合并酒精性脂肪肝的患者在临床上患上相关病症的概率较高,经常出现的病症有高血压,脂代谢紊乱等,并且与胰岛素抵抗也有着密切的关系,同时这类患者患上心血管疾病的几率也大大增加。

Objective The main related factors in patients with nonalcoholic fatty liver disease in patients with type 2 diabetes in clinical treatment the main factor to be considered is the relationship between insulin resistance and cardiovascular disease. Methods Our hospital is the main method for retrospective analysis of patients in the past,from 2010 to 2012 in the hospital for treatment of patients with the disease,the treatment for type 2 diabetes patients,retrospective analysis in 100 cases,the analysis process,the 100 patients according to the disease is divided into 2 group,a group is combined with nonalcoholic fatty liver disease in our hospital,called the experimental group,the other group was not associated with alcoholic fatty liver,this group of patients as control group,two groups of patients were analyzed and unified integration,including the 100 cases of patients with general information,blood lipid levels islet function,etc. Then the comparison between the experimental group and control group differences. Results The experimental group as compared with control group,the content of experimental group patients alanine aminotransferase and gamma-glutamyl transpeptidase is higher, the content of serum three triglycerides were higher, level and insulin also increased,so that we can see clearly that cerebrovascular disease patients and the generation of Xie Fangmian＇s symptoms of disease incidence was significantly higher than that of the control group,in the actual comparison, with statistical difference. Conclusion Patients with type 2 diabetes mellitus complicated with nonalcoholic fatty liver disease in the clinical probability of suffering from related disorders is relatively high,often appear symptoms of hypertension,lipid metabolic disorder and insulin resistance,and also have a close relationship,this kind of patients suffering from cardiovascular disease greatly increased the chance.