期刊文献+

冠状动脉病变程度与脑钠肽及高敏C-反应蛋白的相关性研究 被引量:8

下载PDF
导出
摘要 目的探讨血清脑钠肽(BNP)、高敏C反应蛋白(hs-CRP)与冠心病患者冠状动脉病变程度的相关性。方法将经冠状动脉造影确诊为冠心病的患者203例纳入该研究,根据病变狭窄程度分为轻度病变组、中度病变组、重度病变组;根据冠状动脉损伤形态分为A型低危病变组;B型中危病变组和C型高危病变组。并选择冠状动脉造影正常的45例患者作为对照组。所有患者均检测血清BNP及hs-CRP,分析其与冠状动脉病变狭窄程度及病变损伤分型的相关性。结果各病变组BNP及hs-CRP明显高于正常对照组(P<0.05),且均与冠状动脉病变狭窄程度及损伤分型成正相关(P<0.05)。结论 BNP及hs-CRP水平随冠状动脉病变狭窄程度及冠脉损伤危险分型的加重而增高,可作为预测冠状动脉病变狭窄程度及病变损伤危险分型的良好指标。
作者 曹伟 吴桂平
出处 《中国现代药物应用》 2013年第18期78-79,共2页 Chinese Journal of Modern Drug Application
  • 相关文献

参考文献6

  • 1Ran TJ, Faxon DP, Gunnar RM, et al. Guidelines for percutaneous transluminal coronary angioplasty.A report of the American College of Cardiology American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures(Subcommitt ee on Percutaneous Transluminal Coronary Angioplasty).Cir culation, 1988, 78:486-502.
  • 2Mulvihill NT, Foley JB. Inflammation in acute coronary syndromes. Heart, 2012, 87:201-204.
  • 3Sehwm'zer R. Schne U. JndeHt P, Grabein K, et al. Prognostic valueand clinical effectiveness of high sensitivity C-reactive protein as a marker in primary preventionof mior cardiac events. Z Efid Fortbild Qual Gesundhwes, 2011, 103:319-329.
  • 4Buckley DI, Fu R, Freeman M, et al.C-reaetive protein oo a risk factor for coronary heart disease:a systematic reviw and metaanalyses for the U.S.Ann Intern Med, 2009, 51:483-495.
  • 5胡大一,杨振华.B型那尿肽的临床应用和最新进展.北京:北京科学技术出版社,2006:14-15.
  • 6Asada J, Tsuji H, lwasaka T, et.al. Usefulness of plasma brain natrluretic peptidelevels in predicting dobutamine induced myocardial ischemia. Am J Cardiol. 2004, 93:702-704.

同被引文献70

  • 1Aderville C, Jacques C, Umberto M, et al. Prealbumin improves death risk prediction of BNP-added Seattle Heart Failure Model : Results from a pilot study in elderly chronic heart failure patients. Int J Cardiol, 2013,168: 3334-3339.
  • 2Bengu T, Ozlem K, Zehra B, et al. Investigation of the monoeyte diapede- sis-related LFA-I and JAM-A gene variants in turkish coronary heart dis- ease patients. Meta Gene ,2014,2 : 1-10.
  • 3Zhang MC, Julia S, Zhang Y, et al. Correlation between coronary plaque burden and heart weight. Pathology-Research and Practice, 2012,208 : 610-614.
  • 4Timu P, Tiia KK, Tuire S, et al. Plasma levels of antibodies against oxi- dized LDL are inherited but not associated with HDL-eholesterol level in families with early coronary heart disease. Atheroselerosis, 2012,224 : 123-128.
  • 5Alban DS,Carl JL, Richard VM. The Impact of Obesity on Risk Factors and Prevalence and Prognosis of Coronary Heart Disease-the obesity Para- dox. Progress in Cardiovascular Diseases,2014,56:401-408.
  • 6Jefferis BJ,Whincup PH,Lennon LT,et al.Physical activity in older men:longitudinal associations with inflammatory and hemostatic biomarkers,N-terminal pro-brain natriuretic peptide,and onset of coronary heart disease and mortality[J].J Am Geriatr Soc,2014,62(4):599-606.
  • 7Li X,Chen C,Gan F,et al.Plasma NT pro-BNP,hs-CRP and big-ET levels at admission as prognostic markers of survival in hospitalized patients with dilated cardiomyopathy:a single-center cohort study[J].BMC Cardiovasc Disord,2014,14(1):67-69.
  • 8Xia J,Qu Y,Shen H,et al.Patients with stable coronary artery disease receiving chronic statin treatment who are undergoing noncardiac emergency surgery benefit from acute atorvastatin reload[J].Cardiology,2014,128(3):285-292.
  • 9Xue Y,Taub P,Iqbal N,et al.Mid-region pro-adrenomedullin adds predictive value to clinical predictors and Framingham risk score for long-term mortality in stable outpatients with heart failure[J].Eur J Heart Fail,2013,15(12):1343-1349.
  • 10Mc Intyre HF.Leveraging guidelines:understanding heart failure,organizing care.Commentary on the 2010 NICE chronic heart failure guideline update[J].Eur J Heart Fail,2011,13(1):14-17.

引证文献8

二级引证文献64

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部