精神分裂症患者肝脏彩超检查的临床价值

Clinical value of color ultrasound detection of liver for schizophrenia patients

目的探讨肝脏彩超在精神分裂症患者中的临床应用价值。方法对156例首次诊断为精神分裂症的患者(病例组)于入院前、治疗6、12个月时行肝脏彩超检查,并与正常对照组150例的检查结果进行比较。结果病例组治疗6个月后肝脏彩超示肝内实质不均匀者占14.1%,脂肪肝者占21.8%。治疗12个月时肝内实质不均匀者占22.4%,脂肪肝者占30.1%。病例组治疗6、12个月后肝脏彩超发现肝内实质不均匀及脂肪肝情况与对照组比较,差异有统计学意义(P<0.01)。病例组中联合用药组治疗6、12个月后肝脏彩超发现肝内实质不均匀及脂肪肝变与单一用药组相比,差异有统计学意义(P<0.05)。结论肝脏彩超检查对指导精神分裂症患者临床用药有较高价值。

Objective To investigate the clinical value ot color ultrasound Oetecnon ot river changes alter using urur~~ for schizophrenia patients. Methods One hundred and fifty six patients （case group） diagnosed as schizophrenia for the first time were detected by color ultrasound before admission, six months and twelve mouths after treatment. Their re- sults were compared with those of normal control group of 150 cases. Results Six months after treatment, the color ul- trasound detection showed that the incidence of intrahepatic unevenness and fatty liver in case group were respectively 14.1% and 21.8%; twelve months after treatment, they were 22.4% and 30.1% respectively. At two above time points, the changes of intrahepatic unevenness and fatty liver in case group had significant difference （P〈O.0I） compared with that of control group. In case group, the changes of intrahepatic unevenness and fatty liver in drug combination group had significant difference has higher value in guiding （P〈0.05） compared with that of single drug group. Conclusion Color ultrasound detection clinical application of medicine for patients with schizophrenia.