中药辨证调理预防髋关节置换术后近期认知功能障碍

Prevention of Recent POCD after Hip Replacement Surgery with TCM Differential Treatment

目的观察术前中药辨证调理对老年人术后近期认知功能障碍(POCD)的预防作用。方法择期行全髋关节置换手术的老年患者46例,随机分为2组:观察组和对照组,每组23例。记录患者术前1d、术后第1天和第7天的简易智能量表(MMSE)得分。结果对照组术后第1天及第7天的MMSE评分较术前降低(P<0.05),而观察组术后第1天及第7天的MMSE评分与术前的评分差异无统计学意义(P>0.05)。观察组术后第1d出现认知功能受损的比例(9%)较对照组(35%)低(P<0.05);术后第7天出现认知功能受损的比例分别为4%和17%,但差异无统计学意义(P>0.05)。结论术前中药辨证调理对老年人髋关节置换术后近期认知功能障碍有预防作用。

Objective To observe the preventive effect of recent postoperative cognitive dysfunction（POCD）on the aged with traditional Chinese medicine （TCM） differential treatment. Methods Forty six elderly patients undergoing elective total hip replacement surgery were randomly allocated into two groups （n=23）according to the treatment：observation group and control group. The mini-mental state examination （MMSE）scores of all the patients were recorded one day before surgery,one day and seven days after surgery. Results The MMSE scores of the control group on the first day and the seventh day after surgery were both lower than that before surgery （P〈0. 05）,but the difference of MMSE scores were not statistically significant in the observation group（P〉0. 05）. The incidence of cognitive impairment on the first day after surgery in the observation group （9%） was lower than that in the observation group （35%）（P〈0. 05）. The difference of the incidence of cognitive impairment on the seventh day after surgery was not statistically significant between the two groups （P〉0. 05）. Conclusion The recent POCD can be prevented by the TCM differential treatment on the aged people before hip replacement surgery.