缺血性脑卒中和颈动脉粥样硬化的相关性及超声影像学分析

Ultrasound study of correlation of ischemic stroke and carotid artery atherosclerosis

目的分析缺血性脑卒中和颈动脉粥样硬化的相关性及超声影像学表现。方法回顾性分析我院2009-05—2012-10收治的80例缺血性脑卒中患者的临床资料,同时选取来我院体检的80例健康者为正常对照组。采用多普勒超声检测仪测量所有患者与健康者的踝臂指数、颈动脉斑块与狭窄情况,并对年龄、性别、血脂水平等相关因素进行分析。结果多因素Logistic回归分析结果显示踝臂指数、高LDL-C水平、颈动脉斑块、颈动脉狭窄≥50%、高血压、糖尿病是缺血性脑卒中发生的独立危险因素(OR=5.202、3.086、5.018、4.938、3.114、3.016、P<0.05)。结论颈动脉粥样硬化是缺血性脑卒中发生的高危因素,超声检查能够较好地了解颈动脉的病变性质,为临床提供治疗依据。

Objective To study the correlation of ischemic stroke and carotid artery atherosclerosis and the ultrasound ima- ging findings. Methods The clinical data of 80 patients with ischemic stroke in our hospital from May 2009 to Oct. 2012 were retrospectively analyzed and considered as the stroke group. Meanwhile, 80 healthy people who accepted physical examination were selected as the control group. Doppler ultrasound detector was used to measure the ankle-brachial index, carotid plaque and stenosis of two groups as well as other relevant factors like age, sex, blood lipid levels. Results Multivariate Logistic re- gression analysis showed that the following indexes were some independent risk factors for the occurrence of ischemic stroke： ankle-brachial index, higher LDL-C level, carotid plaque, carotid stenosis of more than 50%, high blood pressure and diabetes （OR=5. 202, 3. 086, 5. 018, 4. 938, 3. 114, 3. 016, P〈0.05）. Conclusion The carotid artery atherosclerotic is a high-risk factor for ischemic stroke. Ultrasound can preferably understand the lesion nature of carotid artery and provide the clinical clue for the treatment.