中西医结合治疗难治性癫痫61例临床观察

Clinical Observation of 61 Cases on Refractory Epilepsia by Combination of Traditional Chinese and Western Medicine

目的:研究中西医结合治疗难治性癫痫的临床效果。方法:将122例难治性癫痫患者随机分为两组,对照组采用传统西药进行治疗,治疗组采用中西医结合方法进行治疗,治疗结束后比较治疗前后两组患者单个月内平均癫痫的发生次数,治疗前后两组患者脑电图的异常率,以及两组治疗方案的临床总有效率。结果:与治疗前比较,治疗后两组患者单个月内癫痫的发作次数明显降低,其中治疗组明显低于对照组,差异有统计学意义(P<0.05);治疗组与对照组在治疗前脑电图异常率基本相当,治疗后均可以明显降低,且治疗组异常率明显低于对照组,差异有统计学意义(P<0.05);治疗组临床总有效率为95.1%,明显高于对照组的73.8%,两组比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗难治性癫痫临床效果显著,减少癫痫发作更明显,临床总有效率更高。

Objective： To study the clinical effect of Traditional Chinese and Western Medicine on refractory epilepsia.Methods： 122 patients with refractory epilepsia were randomly divided into treatment and control group.Patients were treated with traditional western medicine in control group and combination of traditional Chinese and western medicine in treatment group.The frequency of epilepsy in one month,abnormal rate of EGG and the total clinical effect were compared after treatment.Results： After the treatment,the frequency of epilepsy in one month was less,and the frequency in treatment group was less than control group;the difference was statistically significant（P0.05）;The abnormal rate of EGG in the two groups were in the same level before treatment;the rate after treatment was lower in two groups,and the abnormal rate of EGG in treatment group was lower than that in the control group（P0.05）.The total effective rate of treatment group was 95.1%,and the rate of control group was 73.8%;the difference was statistically significant between the two groups（P0.05）.Conclusion： The combination of Traditional Chinese and Western Medicine shows satisfactory clinical efficacy on refractory epilepsy,can reduce the frequency of epilepsy and provide well clinical effective rate.