腹腔镜子宫次全切除术保留子宫动脉上行支对卵巢功能的影响

The impact of intact ascending branch of uterine artery in laparoscopic subtotal hysterectomy on ovarian function

目的:探讨腹腔镜保留子宫动脉上行支的子宫次全切除术对卵巢功能的影响。方法:选择2011年6月至2012年6月因妇科良性疾病行子宫次全切除术并保留卵巢的患者50例,随机分为两组,对照组行传统腹腔镜子宫次全切除术,研究组行腹腔镜保留子宫动脉上行支的子宫次全切除术。分别于术前1个月及术后1个月、3个月、6个月卵泡期抽取患者静脉血2 ml,测定血清雌二醇E2、卵泡刺激素FSH、黄体生成素水平LH。结果:与术前相比,对照组患者术后血清E2、FSH、LH差异均有统计学意义(P<0.05);研究组差异无统计学意义(P>0.05)。结论:腹腔镜保留子宫动脉上行支的子宫次全切除术是安全的,可在一定程度上减慢子宫次全切除术后卵巢的过快衰竭。

Objective： To investigate the impact of intact ascending branch of uterine artery in laparoscopic subtotal hysterecto- my on ovarian function. Methods ： Fifty patients who underwer.t laparoscopic subtotal hysterectomy because of benign gynecological dis- eases from Jun. 2011 to Jun. 2012 were selected and randomly divided into two groups. The patients of control group underwent tradi- tional laparoscopic subtotal hysterectomy, and the research group underwent laparoscopie subtotal hysterectomy preserving ascending branch of uterine artery. 2 ml blood was collected to detect the serum estradiol （ E2 ）, follicle stimulating hormone （ FSH ） and luteini- zing hormone （LH） levels during the follicular phase of one month before the surgery and one month, three months, six months ＇after op- eration. Results ： The serum level of E2 , FSH, LH were significantly different between preoperative and postoperative data in control group （P 〈 0.05 ） ;The serum level of E2, FSH, LH were not significantly different in research group between preoperative and postoper- ative period （ P 〉 O. 05 ）. Conclusions ：The intact ascending branch of uterine artery in laparoscopic subtotal hysterectomy is safe, and can slow down postoperative ovarian failure after subtotal hysterectomy.