间质性肺疾病的临床特点影像学特征及病理类型分析

The clinical characteristics of interstitial lung disease,imaging characteristics and pathologic types of analysis

目的了解间质性肺疾病的临床特点、影像学特征和病理类型。方法对18例间质性肺疾病患者的临床表现、胸CT或高分辨率CT(HRCT)、肺组织病理特点进行分析。结果 18例患者均有咳嗽,其中12例伴有呼吸困难,4例肺内可闻及湿啰音,3例有杵状指趾。胸CT或HRCT示:15例以磨玻璃影为主,2例弥散性细小结节影,1例多发实变影。据病理改变,18例间质性肺炎包括非特异性6例,急性3例,淋巴细胞性1例,未分化型1例,隐源性机化性肺炎2例,呼吸性细支气管炎伴间质性肺炎1例,弥散性泛细支气管炎2例,肺泡微石症、类脂性肺炎各1例。结论间质性肺疾病是一组异质性疾病,临床表现以咳嗽、呼吸困难为主,胸部影像学以磨玻璃影为主,不同的间质性肺疾病病理表现各异。

Objective To understand the clinical characteristics of interstitial lung disease, imaging characteristics and pathologic types~ Methods To diffuse pulmonary disease in 18 patients clinical manifestations, Chest CT and high resolution CT （HRCT） and lung tissue pathology characteristic carries on the analysis.Results Clinical manifestations： 18 cases were cough, 12 eases with have dit^ficulty breathing, audible and wet tale in the 4 cases d lungs, 3 cases with finger clubbing toe. Chest CT and HRCT shows： 15 eases with ground glass shadow is given priority to,2 cases of di^se small nodular shadows, 1 case of multiple consolidation shadows. According to the pathological changes, 18 eases of interstitial pneumonia included in 6 cases of nonspecific interstitial pneumonia （NSIP） and acute interstitial pneumonia （AIP） in 3 patients, hidden source sex machine pneumonia in 2 cases, 1 lymphocytic interstitial pneumonia, respiratory brenchiolitis associated with interstitial pneumonia （RBILD） in 1 case, undifferentiated type, 1 case of interstitial pneumonia, g cases including diffuse extensive bronchiolitis in 2 cases, alveolar micro stone disease in 1 case, lipid pneumonia in 1 case. Conclusion Interstitial lung disease is a group of heterogeneous diseases. Lack of characteristic clinical manifestation, main pedormance for cough, difficulty breathing. Lung imaging sample ground glass shadow as the main change. Different interstitial lung disease pathology behave differently.