摘要
自组装膜是有机分子反应活性头基与固体界面之间自发反应形成的稳定、有序、紧密堆积的超薄膜结构,在材料科学、分子化学、生物医学、工业耐磨防腐等诸多领域具有广泛的应用前景。该文就自组装膜技术在改进生物材料表面的生物相容性、设计生物传感器、发挥药物缓释功能和制备抗菌涂层等方面的应用作一综述。
Self-assembled menolayers （SAMs） is a stable, orderly and close-packing ultrathin membrane structres which is formed by spontaneous and continuous reacting between the organic molecular reactivity head and solid interfaces. SAMs has already widely used in material science, molecular chemistry, biomedicine as well as industry for wear-resistance and anti-corrosion and so on. In this paper, the application of SAMs in the surface modification of biomaterials were reviewed, mainly including improving biocompatibility on the surface of biomaterials, designing biosensors, developing drug delayed release function and preparing antibacterial coating.
出处
《中国骨科临床与基础研究杂志》
2013年第2期109-114,共6页
Chinese Orthopaedic Journal of Clinical and Basic Research
基金
国家自然科学基金面上项目(81271957)
全军医学科学技术研究"十二五"计划面上项目(cws11c268)
关键词
自组装膜
生物相容性材料
生物传感技术
药物植入物
迟效制剂
抗感染药
局部
涂层
Self-assembled menolayers
Biocompatible materials
Biosensing techniques
Drug implants
Delayed-action preparations
Anti-infective agents, local
Coating
