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右美托咪定用于全身麻醉后减少术后阿片类药物用量的Meta分析 被引量:6

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摘要 用Meta分析的方法对右美托咪定用于全身麻醉后减少术后阿片类药物用量,减轻患者疼痛情况和降低不良反应发生率的效果进行系统评价。结果显示,右美托咪定不仅可以减少术后阿片类药物的消耗量,减轻患者术后的疼痛情况,还可以降低术后恶心[OR=0.35,95%CI(0.23,0.53)]、呕吐[OR=0.41,95%CI(0.24,0.70)]、瘙痒[OR=0.37,95%CI(0.19,0.68)]、寒战[OR=0.17,95%CI(0.03,0.92)]等不良反应的发生率,且不增加低血压[OR=13.68,95%CI(0.71,262.17)]和心动过缓[OR=2.45,95%CI(0.87,6.90)]的发生率。在苏醒指标上,右美托咪定组与对照组无统计学差异。
出处 《药学与临床研究》 2013年第4期377-382,共6页 Pharmaceutical and Clinical Research
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参考文献25

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