摘要
血小板粘附、激活和聚集是栓塞性疾病的主要环节,缺血性脑卒中急性期的抗血小板治疗也因此扮演了极为重要的角色。近年来,随着实验室水平的提高以及多项大型临床试验结果的揭盲,人们对抗血小板药物有了更深一步的了解。本文就各种抗血小板药物、相关实验室研究以及临床试验进行综述。
Platelet adhesion, activation and aggregation subsequently play important roles in the pathogenesis of thromboembolic diseases. Antiplatelet therapy, herein, acts a pivotal role for the treatment of acute ischemic stroke. Development of modern experimental technology and evidences established on some recent randomized controlled trials ( RCTs ) shed new light on the utilization of the antiplatelet agents. This review discussed the application of classic, novel and combined antiplatelet strategies, as well as their RCTs evidences.
出处
《中华脑血管病杂志(电子版)》
2013年第3期23-28,共6页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
基金
东莞市科技局重点科技项目(10500270308)
广东省医学科研基金(B2008173)