中医药治疗宫颈癌研究进展

Research progress in traditional Chinese medicine treatment of cervical carcinoma

近年来宫颈癌发病率有着逐渐年轻化的趋势,西医针对宫颈癌主要采用手术及术后放化疗的治疗方式,但随之而来的是一系列的术后并发症以及放化疗所带来的不良反应。祖国医学对于宫颈癌的发生发展有着较为独特的认识,认为宫颈癌发病原因主要在于房劳多产、饮食不节,情志不舒等所致的湿热、痰浊、瘀毒等邪气外袭胞宫,郁而不解,损伤冲任带脉,根本原因则是正虚邪实。近年来众多研究表明,中药对于促进宫颈癌细胞凋亡,减少化放疗的副作用有较好的效果。但相关基础研究仍较薄弱,许多中药的有效成分及发挥作用的机制不甚明了,复方的研究缺乏多中心、大样本的长期随访研究。

The incidence rate of cervical cancer has got a gradually younger trend in recent years. Operation and postoperative chemotherapy and radiotherapy are currently the main treatment for cervical cancer . The Chinese medicine has a special knowledge of the occurrence and development of cervical cancer,which mainly lies in the damp heat, phlegm and blood stasis attacking the uterus caused by unre-strained sex, improper diet, sluggish emotion and so on. They are depressed and confused, which injure the Chong、 Ren and Dai channel. But the essential reason is the asthenia healthy qi and sthenia pathogenic factor syndrome . In recent years, many studies showed that the traditional Chinese medicine （TCM） has got a good effect of promoting the apoptosis of cervical cancer cells and can also reduce the side effects of chemotherapy and radiotherapy . But the related basic research is still weak and the effective ingredients and mechanism of TCM are still not clear enough. Moreover, compound studies lack a muhicenter, large sample of long-term follow-up studies.