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炎症性细胞因子TGF-β超家族及其在肝细胞癌中的作用 被引量:4

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摘要 肝细胞癌(HCC)严重威胁人类健康,肝炎病毒、过量酒精摄人及黄曲霉毒素等是其发生、发展的重要致病因素。转化生长因子β(TGF-β)家族是一个多功能的生长因子超家族,在生命活动中起着广泛的调节作用。涉及形态发生、胚胎发育、免疫凋节、创伤疮合、炎症及肿瘤。近年来研究表明,长期慢性炎症与肿瘤关系密切,而TGF—β在HCC的发生、发展过程中,表现出较为特殊的作用。因此,对TGF-β超家族的深入研究,将会为临床肝脏肿瘤诊疗水平的进一步提高奠定良好的基础。
作者 王晗 刘俊杰
出处 《肝脏》 2013年第8期572-575,共4页 Chinese Hepatology
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