米索前列醇阴道给药用于早孕人工流产的临床分析

Clinical analysis of vaginal administration of misoprostol for artificial abortion

目的探讨人工流产术前应用米索前列醇阴道给药的临床效果。方法将我院自愿要求终止妊娠的患者112例,随机分为观察组56例和对照组56例。对照组采用2%利多卡因局部麻醉,观察组在对照组基础上于阴道后穹窿放置米索前列醇400μg麻醉,记录两组患者镇痛疗效对比,及宫颈管管径和术中出血量。结果观察组总有效率达92.9%,明显优于对照组且差异有统计学意义(x2=4.752,P<0.05);观察组宫颈管管径大于对照组但差异无统计学意义(P>0.05),术中出血量明显少于对照组,差异有统计学意义(P<0.01)。结论阴道放置米索前列醇用于无痛人流术镇痛效果明显,可有效扩张宫颈,减少术中出血,减轻患者痛苦,不良反应小,是一种较为理想的无痛人流麻醉方式。

Objective To investigate the application of misoprostol before artificial abortion vaginal administration of clinical effect of drug. Methods The voluntary termination of pregnancy in 112 cases were randomly divided into the observation group 56 cases and control group with 56 cases. The control group using 2% lidocaine local anesthesia, the observation group on the basis of the control group in the misoprostol vaginal fornix 400 ~L g anesthesia, analgesia in patients with two groups curative effect comparison of records, and cervical tube diameter and the amount of bleeding. Results The total effective rate of observation group was 92.9%, significantly higher than that of the control group and the difference was statistically significant （x2=4.752, P 〈 0.05）; observation group of cervical tube diameter larger than that of the control group but without significant difference （P ：〉 0.05）, bleeding was significantly less than that in the control group, there were significant differences （P 〈 0.01）. Conclusion Misoprostol for painless induced abortion analgesia effect is obvious, can be effective for cervical dilatation, reduce bleeding, reduce the suffering of patients, with less adverse reactions, is an ideal painless anesthesia.