妊娠期糖尿病孕妇空腹血糖及餐后1小时血糖、血脂、血清胰岛素水平与妊娠结局相关性分析

Fasting blood sugar and 1 hour postprandial blood glucose levels,lipid levels,serum insulin levels and pregnancy outcomes in pregnant women with GDM

目的探讨分析妊娠期糖尿病（GDM）孕妇空腹血糖及餐后1h血糖水平、血脂水平、血清胰岛素水平与妊娠结局的临床相关性情况。方法选取2011年2月-2012年8月我院进行常规产前检查的40例健康孕妇作为对照组，将同期确诊为GDM的42例孕妇作为观察组，检测两组孕妇的空腹血糖及餐后1h血糖水平、血脂水平、血清胰岛素水平并比较两组孕妇的妊娠结局差异。结果观察组的空腹血糖及餐后1h血糖水平、血脂水平、血清胰岛素水均明显高于对照组；且观察组巨大儿、新生儿高胆红素血症、新生儿低血糖等并发症发生率显著高于对照组（P〈0．05）。结论GDM孕妇空腹血糖及餐后1h血糖水平、血脂水平、血清胰岛素水平增加了围生儿的风险，值得临床注意、及早干预。

Objective To investigate gestational diabetes mellitus （GDM） fasting glucose and clinical relevance of one hour postprandial blood glucose levels,lipid levels,serum insulin levels and pregnancy outcomes. Methods From February 2011 to August 2012, choosing 40 healthy pregnant women as a control group,chosing GDM 42 cases of pregnant women as the observation group,detected in both groups of pregnant women,fasting blood glucose and meal 1 hour after the blood sugar level,blood lipid levels, serum insulin levels and compared the two groups differences in pregnancy outcomes of pregnant women. Results Observation group one hour fasting glucose and postprandial glucose levels,lipid levels,serum insulin levels were significantly higher,observation group of huge children,neonatal hyperbilirubinemia,neonatal hypoglycemia was significantly higher incidence of complications（P 〈 0.05）. Conclusion GDM pregnant women fasting blood sugar and 1 hour postprandial blood glucose levels,lipid levels,serum insulin levels increase the risk of perinatal children,worthy of clinical attention to early intervention.