期刊文献+

Excel支架治疗冠心病合并糖尿病患者的安全性和有效性 被引量:5

下载PDF
导出
摘要 目的通过与进口雷帕霉素药物洗脱支架(Cypher)比较,观察国产雷帕霉素药物洗脱支架(Excel)在冠心病合并糖尿病患者中应用的安全性和有效性。方法回顾性分析择期PCI并置入雷帕霉素药物洗脱支架的冠心病合并糖尿病患者135例,根据置入支架的种类,分为Excel组(试验组)和Cypher组(对照组)。术前术后常规用药,术后进行随访,观察患者术中并发症的发生情况及术后1个月、3个月、半年,1年临床主要不良心脏事件(MACE)的发生情况,并于术后1年进行冠脉造影随访,观察冠状动脉病变情况。结果一般临床资料情况:2组在性别、年龄、身高、体重、危险因素(高血压、血脂异常、吸烟史、饮酒史)、临床表现(稳定型心绞痛、不稳定型心绞痛、急性心肌梗死、陈旧性心肌梗死的患病例数)、冠状动脉病变类型(A型、B型、C型)、冠脉病变支数、置入支架情况(支架的直径、长度)上比较,差异无统计学意义(P>0.05)。术中并发症情况:试验组与对照组在冠脉急性闭塞、冠脉穿孔、冠脉夹层、恶性心律失常、死亡方面均发生0例,2组患者置入支架的安全性相似。术后1年内的随访:2组1年内复发心绞痛急性心肌梗死心源性死亡比较差异无统计学意义(P>0.05)。结论 Excel支架治疗冠心病合并糖尿病患者的安全性和有效性与Cypher支架相似,但仍需大样本随机对照临床研究加以进一步证实。
出处 《河北医药》 CAS 2013年第20期3067-3069,共3页 Hebei Medical Journal
  • 相关文献

参考文献14

  • 1Macin SM, Pema ER, Colonel ML, et al. Influence of admission glucose level on long-term prognosis in patients with acute coronary syndrome. Rev Esp Cardio1,2006,59 : 1268-1275.
  • 2于梅.冠心病患者并发糖代谢异常的临床研究[J].中国煤炭工业医学杂志,2006,9(8):820-821. 被引量:9
  • 3Stein B, Weintmub W, Gebhart S, et al. Influence of diabetes mellitus on early and late outcome after percutsneous translumellitus coronary angio- plasty. Circulation, 1995,91:979-989.
  • 4Abizaid A, Costa MA, Centemero M, et al. Clinical and economic impact of diabetes menitus on percutaneous and surgical treatment of muhivessel coronary disease patients: insights from the Arterial Revascularization Therapy Study ( ARTS ) trial. Circulation,2001,104 : 533-538.
  • 5Mosseri I, Nahir M, Rozenman Y, et al. Diffuse narrowing comnary arter- ies in diabetic patients:the earliest phase of coronary anery disease. Car- diology, 1998,89:103.
  • 6Nakashima H, Akiyama Y, Tasaki H, et al. Comnary microvascular dys- function in coronary artery disease associated with glucose intolerance. Cardiol, 1997,30:59.
  • 7Cutlip DE, Chanhan MS, Balm DS, et al. Clinical restenosis afet coronary stenting: perspectives from multicenter clinical triM. Am Coil Cardiol, 2002,40:2082-2089.
  • 8Abizaid A, Komowski R, Mintz GS, et al. The influence of diabetes metli- tus on acute and late clinical outcomes following coronary stent implanta- tion. Am Coil Cardio,1998 ,32 :584-589.
  • 9Elezi S, Kastrati A, Pache J, et al. Diabetes mellitus and the clinical and angiographic outcome after coronary stent placement. Am Coil Cardiol, 1998,32 : 1866-1873.
  • 10Rensing B J, Hermans WR, Vos J, et al. Luminal narrowing after percuta- neous transluminal coronary angioplasty : a study" of clinical, procedural, and lesional factors related to long-term angiographic outcome. Coronary Artery Restenosis Prevention on Repeated Thromboxane Antagonism (CARPORT) Study Group. Circulation, 1993,88:975-985.

二级参考文献6

  • 1Expert Panel on Detection.Evaluation,and Treatment of High Blood Cholesterol in Adults.Executive summary of the third report of The National Cholesterol Education Program (NECP)Expert Panel on Detection,Evaluation,and Treatment of High Blood Cholesterol in Adults(Adult Treatment PaneⅢ)[J].JAMA,2001,285:2486-2497
  • 2Malmberg K,Norhammar A,Wedel H,et al.Glucometabolic state at admission:important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction.Long-term results from the diabetes and insulin-glucose infusion in acute myocardial infarction (DIGAMI) study[J].Circulation,1999,99:2626-2632
  • 3Norhammar AM,Ryden L,Malmberg K.Admission plasma glucose.Independent risk factor for long-term prognosis after myocardial infarction even in non diabetic patients[J].Diabetes Care,1999,22:1827-1831
  • 4Capes SE,Hunt D,Malmberg K,et al.Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes:a systematic overview[J].Lancet,2000,355:773-778
  • 5Bartnik M,Malmberg K,Hamsten A,et al.Abnormal glucose tolerance-a common risk factor in patients with acute myocardial infarction in comparison with population-based controls[J].J Int Med,2004,256:288-297
  • 6Norhammar A,Tenerz A,Nilsson G,et al.Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus:a prospective study[J].Lancet,2002,359:2140-2144

共引文献8

同被引文献52

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部