先天性肾病综合征并脑梗死一例

Congenital Nephrotic Syndrome Complicated by Cerebral Infarction: Report of One Case

先天性肾病综合征是新生儿在出生3个月内出现大量蛋白尿、水肿、低蛋白血症的肾病综合征表现。可分为继发性和原发性。继发性多继发于围生期感染,原发性多与基因突变有关。本文报道的此例新生儿倾向于原发性,且同时合并脑梗死,临床上较少见。笔者旨在通过对其临床表现、实验室检查及影像学检查结果的分析,加强临床医师对该病的认识。

Congenital nephrotic syndrome （CNS）, a nephritic syndrome of massive proteinuria, edema, hypoalbu- minemia occurring within 3 months after neonatal births, can be divided into primary and secondary. Secondary CNS is more common in secondary perinatal infection, primary CNS is more likely related to genic mutation. This case is apt to primary, complicated by cerebral infarction, which is rare clinically. This paper analyzes CNS clinical manifestations, laboratory tests and imaging findings to strengthen clinical physicians＇ awareness of this disease.