参松养心胶囊对冠心病患者心率变异性和QT离散度的影响

Effect of senate pine spiritual cultivation capsule on heart rate variety and QT dispersion of patients with coronary heart disease

目的探讨参松养心胶囊对冠心病患者心率变异性(heart rate variety,HRV)和QT离散度(QT dispersion,QTd)的影响。方法将192例冠心病患者随机分为参松养心胶囊治疗组(98例)和对照组(94例),分别观察两组患者治疗前后HRV相关指标和QTd、校正后QTd(QTcd)的变化。结果与治疗前相比,两组患者治疗后HRV相关指标均升高;QTd、QTcd均显著减少,以参松养心胶囊治疗组的效果更为明显。两组间比较,差异有统计学意义(P<0.01)。结论参松养心胶囊可有效提高HRV相关指标,降低QTd,起到改善自主神经平衡性、改善预后、防治室性心律失常的作用。

Objective To discuss the effect of senate pine spiritual cultivation capsule on heart rate variety （HRV） and QT dispersion （QTd） of patients with coronary heart disease （CHD）. Methods Randomly divide 192 CHD patients into observation group（98 cases） treated with senate pine spiritual cultivation capsule and control group （94 cases） , and then observe the changes of indexes related to HRV, QTd and corrected QTd （QTed） between the two groups respectively before and after the treatment. Results After the treatment, indexes related to HRV all increased while QTd and QTcd both decreased with a comparatively significant decrease in the observation group. The differences between the two groups were statistically significant （P 〈 0.01 ）. Conclusion It indicated that senate pine spiritual cultivation capsule could effectively raise indexes related to HRV and reduce QTd, and thus improve the balance of autonomic nerve and prognosis and prevent ventrieular arrhythmia.