摘要
目的观察加味六味地黄汤治疗2型糖尿病气阴两虚证的临床疗效。方法将初诊为2型糖尿病的52例患者随机分为两组,每组各26例。对照组采用格列美脲片口服治疗,治疗组在对照组基础上加用加味六味地黄汤联合治疗。两组均连续治疗12周,观察患者治疗前后症状变化,监测空腹血糖、餐后血糖、糖化血红蛋白及甘油三酯、总胆固醇。另对比治疗前后不良反应发生率。结果治疗组总有效率为88.50%,不良反应率为3.85%,对照组总有效率为69.20%,不良反应率为7.7%,治疗组总有效率优于对照组(P<0.01);且监测空腹血糖、餐后血糖及糖化血红蛋白均显示治疗组优于对照组(P<0.01),安全性差异无统计学意义。结论加味六味地黄汤治疗2型糖尿病气阴两虚证临床疗效确切且安全性良好。
Objective To observe the clinical efficacy on type -2 diabetes differentiated as qi and yin deficiency treated with modified Liuwei Dihuang Tang. Methods Fifty - two cases of type - 2 diabetes at the first visit were randomized into two groups ,26 cases in each one. In the control group, Glimepiride Tablets were used for oral administration. In the treatment group, on the basic treatment as the control group, the mod-ified Liuwei Dibuang Tang was supplemented. The treatment was given continuously for 12 weeks in the two groups. The symptoms were observed before and after treatment. FBG ( fasting blood - glucose ), PBG ( post-prandial blood glucose), HbALe ( glycosylated hemoglobin), TG ( triglyceride ) and TC ( total cholesterol ) were monitored. Additionally, the incidence rate of adverse reaction was compared before and after treatment. Re- sults The total effectively rate was 88.50% and the incidence rate of adverse reaction was 3.85% in the treatment group. The total effective rate was 69.20% and the incidence rate of adverse reaction was 7.7% in the control group. The total effective rate in the treatment group was better than that in the control group ( P 〈 0.01 ). The levels of FBG,PBG and HbALe in the treatment group were superior to the control group( P 〈 0.01 ). The difference in the safety was not significant. Conclusion The modified Liuwei Dihuang Tang a-chieves the definite clinical efficacy and good safety in the treatment of type - 2 diabetes differentiated as qi and yin deficiency.
出处
《世界中西医结合杂志》
2013年第9期950-951,972,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
加味六味地黄汤
糖尿病
气阴两虚证
Modified Liuwei Dihuang Tang
Diabetes
Qi and Yin Deficiency Pattern/Syndrome