爱尔碘皮肤消毒后最佳穿刺时间的研究

Study on optimal puncture time after skin disinfection with Aierdian

目的探讨爱尔碘皮肤消毒效果满意的最佳穿刺时间。方法随机抽取静脉输液患者500例次，分5批次进行对照试验。每组100例次，用统一大小的棉棒浸相同量的爱尔碘消毒液，从注射中心由内向外旋转，将药液涂抹均匀，面积5cm×5cm以上，分别在消毒后10～20S（1组）、21～30S（2组）、31～40s（3组）、4i～50s（4组）、51～60S（5组）时，用无菌管型棉拭子取样做细菌培养，观察消毒效果满意的最佳穿刺时间。结果爱尔碘皮肤消毒后10～20s、21～30s细菌培养结果阴性，31～40S细菌培养结果阳性率低，与前两组比较无差异（均P〉0．005）；随着时间的延长，41～50S、51～60S细菌培养阳性率逐渐增加，其中51～60S与前4组比较，差异有统计学意义（均P〈0．005）。结论爱尔碘皮肤消毒后20S完全蒸发，消毒后10～30s细菌培养结果为阴性。因此，建议穿刺应控制在消毒后20～30s进行效果最佳。

Objective To investigate the optimal puncture time after skin disinfection with Aierdian. Methods We randomly selected 500 venous punctures, which were sequenced and divided into 5 hatches, with 100 punctures in each batch. Before the punctures, we used a cotton swab saturated with Aierdian to disinfect the puncture site from center out-ward in circular motion for over 5 cm in diameter, then we employed a sterile cotton-tip swab to stroke the disinfected skin for specimen after 10--20 s （the 1st batch）, 21--30 s（the 2nd batch）, 31--40 s（the 3rd batch）, 41--50 s（the 4th batch）, and 51--60 s（the 5th batch） ,respectively. Then we immediately placed the cotton-tip swab into a culture tube, which was later sent to the lab for microbiologic testing. Results Micro- biologic cultures were tested negative for the the 1st batch （10--20 s） and the 2nd batch（21--30 s）; for the 3rd batch（31--40 s）, only a few cultures were tested positive; positive cultures showed an upward trend in the 4th batch（41--50 s）, and the 5th batch （51--60 s） ,with the last batch significantly higher than any of the previous 4 groups （P〈0. 005 for all）. Conclusion Given that it takes the Aierdian to dry in 20 s of disinfection, and microbiologic cultures are tested negative within 10--30 s after skin disinfec- tion with Aierdian, it is recommended that we should perform venous puncture within 20--30 s after skin disinfection.