参芎葡萄糖注射液对急性心肌梗死冠脉介入治疗后心室重塑的影响

The Effect of Shenxiong Glucose Injection for Acute Myocardial Infarction Ventricular Remodeling of the Coronary Intervention

目的:探讨参芎葡萄糖注射液对急性心梗冠脉介入治疗后心室重塑的影响。方法:2011年6月-2012年6月本院心内科收治的急性心梗患者118例,随机分为两组,对照组采取常规药物治疗并行PCI术,观察组在此基础上加用参芎葡萄糖注射液,比较两组治疗后心室重塑的影响。结果:两组术后4周心脏超声各项指标较术后1周均有明显改善(P<0.05);观察组术后1周和术后4周LVESV、LVEDV和LVEF指标与对照组比较差异均具有统计学意义(P<0.05)。结论:参芎葡萄糖注射液对急性心梗冠脉介入治疗后心室重塑效果较好,可明显改善心室功能,抑制心室重塑,具有较好的临床应用价值。

Objective：To investigate the effect of for acute myocardial infarction ventricular remodeling of the coronary intervention. Method：118 cases were the patients with acute myocardial infarction from June 2011 to June 2012 in cardiology of our hospital,and they were randomly divided into two groups,all of the patients were given regular medications parallel PCI while the observation group was given Shenxiong glucose injection based on the control group. The ventricular remodeling of the two groups was compared after the treatment. Result：After 4 weeks,the echocardiographic indicators showed significant improvement than 1 week（P〈0.05）;after 1 week and 4 weeks,the LVESV,LVEDV and LVEF indicators of the observation group were significant differences compared with which of the control group（P〈0.05）. Conclusion：Shenxiong glucose injection for acute myocardial infarction ventricular remodeling of coronary intervention can significantly improve ventricular function,inhibit ventricular remodeling,and it has better clinical value.