蛋白质折叠的三维计算机模拟

Three-dimensional Computer Simulation for Protein Folding

介绍了计算机模拟蛋白质的三维模型．利用混合遗传算法对模型问题进行了模拟计算，获得了由２７个氨基酸残基组成的肽链的能量最小的折叠构象．计算结果表明，对于蛋白质折叠的三维晶格模型而言，混合遗传算法是很有效的．

A three--dimensional model of protein folding using computer simulation is introduced. The hybrid genetic algorithm is employed in simulated calculation for the model. A lowest energy structure of peptide chain composed of 27 residues is attained. The computation results indicate that the hybrid genetic algorithm is effective for protein folding using a three--dimensional lattice model.