功能MRI:最先进方法的简要回顾和展望(英文)

fMRI: a brief review and outlook on the state-of-the-art methodology

功能MRI(fMRI)起始于20世纪90年代初,它能够敏感地测量由脑激发而引起的血氧浓度变化。在经历了20年的高速发展后,fMRI在大脑研究领域中已经奠定了其不可替代的地位。随着科技的进步,包括硬件、脉冲序列、实验设计以及数据分析方法上的不断更新,fMRI在下一个10年应该会有更广泛的应用。在此文中,针对现状来探讨一下相关的先进技术,例如高清功能成像、脑连接成像、多模成像;并展望将来的发展方向,例如它们在临床医学甚至在社会科学方面的应用。

ince the early 1990＇s,functional Magnetic Resonance Imaging（fMRI） has seen explosive growth over the past two decades,and has become a dominant technique in modern neuroscience research.Recent technological advances,including those in imaging hardware,pulse sequences,experimental design,as well as analysis strategies,ensure that fMRI will see continued growth and expansion into even broader applications.In this report,we will briefly review the current state of MRI technological research,such as high-resolution imaging,connectome imaging,and multi-modal imaging.We will also briefly discuss a few possible future directions of fMRI,ranging from its applications in clinical to social sciences.