植物活力素的亚急性毒性试验研究

The Studies of Subacute Toxicity on Plant Mineral Elements in Rats

用 30天短期喂养试验方法对植物活力素进行了亚急性毒性探讨。结果显示 :2 0 mg/ kg剂量能显著促进大鼠体重增长及提高 Hb的含量与食物利用率 ,80 mg/ kg剂量作用次之 ,而32 0 mg/ kg剂量则使雄性大鼠体重下降和雌性血清 GPT升高。提示植物活力素的作用是双重的 ,其 30天喂养试验的最大无毒作用剂量是 80 mg/ kg,适宜剂量为不大于 2 0 mg/

The author carried on the Subacute Toxicity by 30-day-feed experiment on Plant Mineral Element (PME).The results showed the PME could increase weight of rats and content of Hb in the group of 20 mg/kg and 80 mg/kg,and improved utilization ratio of food in 20 mg/kg dosage.On the other hand,toxicities were displayed in 320 mg/kg dosage.The results suggest that the PME is dual-effect that varies from dosage to dosage.No-observed-toxical-effect dosage of the PME is 80 mg/kg and its suitable dosage is 20 mg/kg in 30-day-feed experiment.