重组人红细胞生成素治疗产科贫血

Recombinant Human Erythropoietin Treatment in Obstetric Anemia Patients

目的 探讨重组人红细胞生成素 (r Hu EPO)对产科贫血的治疗效果。 方法 贫血患者单次静脉注射 r Hu EPO80 0 0 IU;贫血患者及对照组均给予口服补充铁剂和叶酸。 结果 无论产前贫血组和产后贫血组血红蛋白均有较明显的回升 (P<0 .0 0 1)。血清铁治疗前后无明显变化 (P>0 .0 5 )。 结论 重组人红细胞生成素治疗产科贫血安全。

Objective To investigate the efficacy of recombinant human erythropoietin(rHuEPO) in treating the anemia in obstrics. Methods 40 antepartum anemia patients and 36 postpartum anemia patients were treated with rHuEPO 8000IU intravenously. Another 40 antepartum and 36 postpartum anemia patients were selected as control. Oral supplementation of iron and folic acid were used both in study and control group. Results The hemoglobin level was increased significantly in the study group than control group both in the prenatal and postpartum anemia patients. ( P<0.001 ) No significant change was shown in the serum ferrite level between the study and control group.( P>0.05 )。 Conclusion rHuEPO therapy for obstetric anemia is effective and safe.