兔VX2移植性肝癌模型的建立和影像学及病理学评价

Establishment,Pathological Evaluation and imaging evaluation of a rabbit transplanted VX2 hepatocarcinoma model

目的:建立兔VX2移植性肝癌模型、探讨其影像学及病理学特点。方法:将50只新西兰大白兔采用移植法建立兔VX2移植性肝癌模型,于移植术后13天行DSA、MRI及病理检查。结果:有48只兔接种成功,其影像学及病理学表现均类似于人类原发性肝癌。结论兔VX2移植性肝癌模型可用于介入栓塞材料的实验研究。

Objective ：To establish the rabbit VX2 hepat^arcinoma model and study the features of imaging and pathology examination. Mmethods： Fifty Newzealand rabbits hepatoearcinoma model were established by VX2 tumor implantation Digital subtraction angiography （DSA）, magnetic resonance imaging （MRI） scanning and Pathology were performed 13 days after implantation. Result：Suececssful implantation was obtained in 48rabbits by the examination of MRI and CT scanning .The imagology and pathology are all similar with human hepatocarcinoma. Conclusion：Rabbit VX2 heptocarcinoma model is suitable for interventional experiment study of the Vascular embolization agent on hepatocarcinoma.