95例住院高龄肺结核临床分析

Clinical analysis of 95 cases inpatients with pulmonary tuberculosis in the senility

目的 探讨高龄肺结核临床特征及治疗和管理措施。方法 对高龄肺结核 (Ⅰ组 )从临床特征、治疗及疗效方面与老年肺结核 (Ⅱ组 )进行对比分析。结果 ( 1)Ⅰ组循环系统并发症、营养不良及伴有 3种以上合并症者均高于Ⅱ组 ,合并糖尿病和咯血者少于Ⅱ组 (P <0 .0 5)。 ( 2 )Ⅰ组初治者空洞病变少 ,复治者病变范围广 ,与Ⅱ组比较有统计学意义 (P <0 .0 5)。 ( 3)Ⅰ组痰菌阳性率低于Ⅱ组 (P <0 .0 5)。 ( 4 )Ⅰ组中三药联合化疗与四药联合化疗近期X线好转率无明显差异 (P >0 .0 5) ,四化毒副反应明显高于三化 (P <0 .0 5)。结论 ( 1)对高龄肺结核应提高警惕并加强管理。 ( 2 )治疗高龄肺结核用药要适量 ,三化方案最佳。 ( 3)两组经合理规律治疗均可取得满意效果。

Objective To investigate clinical features,proper treatment and management methods of pulmonary tuberculosis in the senility.Methods A comparison of clinical features,treatment,effect and compliance in cases of pulmonary tuberculosis among 95 senilities(≥80 years) and 80 old patients(60～80 years) was performed.Results (1)Complication of circulatory diseases,innutrition and the number of patients who had more than 3 varieties of complications were larger in group Ⅰthan in group Ⅱ.(2)Cavitary cases of new cases in group Ⅰ were less than that of group Ⅱ( P<0.05 ).(3)The positive rate of sputum was lower in group Ⅰthan that of groupⅡ( P<0.05 ) and the effect of treatment were no significantly differences from group Ⅱ( P>0.05 ).(4)The improvement of X-ray was no significantly difference between three drugs and four drugs( P>0.05 ),but the side effect with four drugs was significantly higher than with three drugs( P<0.05 ). Conclusion (1)It is necessary to pay more attention to the senility with pulmonary tuberculosis to avoid delaying diagnosis and trentment.(2)The treatment to senility with pulmonary tuberculosis need proper doses and three drugs project is the best.(3)The effect was satisfied if they received regular treatment both in group Ⅰ and Ⅱ.