摘要
目的探讨络风宁1号方治疗冠心病不稳定型心绞痛(UA)的疗效。方法采用随机对照的研究方法,将60例不稳定型心绞痛合格病例分为治疗组(基础西药治疗+络风宁1号颗粒剂)和对照组(基础西药治疗),服药4周后,观察两组患者心绞痛发作情况及心绞痛积分变化,同时使用ELISA法检测患者用药前后血脂水平及血清炎症因子白细胞介素-6(IL-6)、基质金属蛋白酶9(MMP-9)的浓度变化。结果治疗组可明显改善患者心绞痛发作情况,与对照组相比有统计学意义(P<0.05)。结论络风宁1号颗粒剂治疗不稳定型心绞痛有一定的临床疗效。
Objective To investigate the effects of Luofengning 1 prescription （LFN - 1） for the treatment of unstable angina pec- toris. Methods Sixty patients with unstable angina pectoris were divided into two groups：Control group treated by routine treat- ment,and treatment group treated by LFN - 1 on the basis of routine treatmenl. After treatment for 4 weeks,angina pectoris attacks and the angina score were observed. Serum interleukin - 6 （IL - 6）, and metalloproteinase - 9 （MMP - 9） were detected with ELISA before and after the treatment. Results Attacks of angina in treatment group was obviously reduced（P〈0. 05）. The overall effect was better than that in control group（P〈0.05）. Conclusion LFN - 1 was effective for unstable angina peetoris.
出处
《中西医结合心脑血管病杂志》
2013年第9期1039-1041,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
