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高海拔地区姜黄对肝硬化大鼠TGF-β1表达的影响 被引量:2

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摘要 目的:探讨姜黄对肝硬化大鼠TGF-β1表达的影响。方法:健康雄性SD大鼠30只,随机分出10只组成对照组。剩余20只组成模型组1及模型组2(建立肝硬化大鼠模型),分别于造模后给以2.5%羧甲基纤维素和姜黄强饲每日一次,连续24周。取大鼠肝脏做病理切片、抽取大鼠血样,并行ELISA法实验。结果:模型组1中TGF-β1在造模后不断升高,至第24周达最高(127μg/L),模型组2与对照组TGF-β1表达差别无统计学意义(P>0.05)。结论:姜黄对肝硬化大鼠TGF-β1的表达有明显抑制作用。
作者 卓玛措
出处 《中国民康医学》 2013年第18期20-20,29,共2页 Medical Journal of Chinese People’s Health
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