出生缺陷二级预防策略的研究

Study on the Secondary Prevention Strategy for Birth Defects

目的:评价、比较出生缺陷的3种二级预防策略的经济学效果,为有效预防先天性残疾提供决策依据。方法:采用决策树模型,对3种策略的成本-效果进行比较。结果:3种策略的出生缺陷检出率分别为82.82%、98.2%、94.50%,策略3成本/效果比最低。结论:高危孕妇增加超声筛查是一种既经济又有效的预防策略。

Objective： To evaluate and compare the economic effectiveness of three strategies of the sec- ondary prevention for birth defects in order to provide the basis for the prevention decision on congenital disa- bilities. Methods： A decision tree model was used to make a decision analysis on the cost-effectiveness of the three strategies. Results： The birth defects detection rates of three strategies were 82.82%, 98. 2%, 94. 50% respectively. The cost of one birth defect detected of the third strategy was lowest. Conclusions： Increasing an ultrasound screening for high-risk pregnant women is an economical and effective strategy to pre-vent birth defects.