几丁糖预防输卵管介入再通术后粘连阻塞的临床应用

The study of Prevention Oviduct Adhesion and Blocking after Interventional and Recanalizational Surgery by Using Chitosan

目的:探讨医用几丁糖预防输卵管介入再通术后粘连阻塞的效果。方法:选择109例阻塞性输卵管介入再通术患者,被随机分为研究组(57例)和对照组(52例),对照组仅作消炎灌注治疗,研究组输卵管开通后作消炎灌注,再注入医用几丁糖。结果:两组阻塞输卵管再通率分别为95.8%、95.6%。手术后一年内,研究组妊娠率为50.8%(33/57),对照组妊娠率25%(13/52)。数据表明,术后两组妊娠率比较差异明显。结论:医用几丁糖能较有效地预防输卵管介入再通术后的再次阻塞。

Purpose Study the cure effects of preventing oviduct adhesion and blocking after interventional and recanalizational sur- gery by using chitosan. Method： 109 cases of patients who had surgery of obstructive tubal interventional recanalization are classified at random into Study Group （57cases） and Treatment Group （52cases）. Treatment of diminishing inflammation infusion is only given to Treatment Group, while chitosan is injected to Study Group after the inflammation diminishing injection after the oviduct opens. Re- sult ： The recanalization rates of blocked oviducts of two groups are respectively 95. 8% and 95.6%. Within 12 months after surgery, the pregnancy of Study Group is 50. 8% （33/57）, and 25% （13/52） of Treatment Group. Evident differences occur to the pregnancy rate after surgery between two groups. Conclusion： chitosan is effective in preventing blocking and edhesion after the surgery of ovi- duct intervention and recanalization.