孟鲁斯特与丙卡特罗二联治疗儿童咳嗽变异性哮喘疗效分析

Analysis of therapeutic effect of montelukast combined with procaterol in the treatment of children with cough variant asthma

目的探讨孟鲁斯特与丙卡特罗二联治疗儿童咳嗽变异性哮喘(CVA)临床效果。方法选取我院门诊及住院治疗CVA患儿180例,随机分为治疗组(A组)和对照组(B组);其中B组患儿单用丙卡特罗治疗;A组患儿在B组治疗基础上,加用孟鲁斯特;比较两组患儿临床改善总有效率,结果 A组临床改善总有效率(98.9%)明显高于B组(75.6%),组间比较差异显著(P<0.05);结论孟鲁斯特与丙卡特罗二联治疗CVA可显著改善临床症状,缩短病程。

Objective To discuss the clinical curative effect of montelukast combined with procaterol in the treatment of children with cough variant asthma. Methods 180 children with CVA in our hospital from May, 2009 to October, 2012 were randomly divided in- to the treatment group （the group A） and the control group （the group B）. All patients were treated with procaterol, and the group A was additionally treated with montelukast. The total effective rate was compared between the two groups. Results The total effective rate was 98.9% in the group A and 75.6% in the group B respectively, and the difference between the two groups was significant （P 〈 0.05 ）. Conclusion The combined treatment of montelukast and procaterol can significantly improve the clinical symptoms and shorten the course of disease.