多层螺旋CT灌注对非小细胞肺癌放、化疗疗效价值运用分析

Analysis of application value of multislice CT perfusion on radio-chemotherapy in the treatment of non-small cell lung cancer

目的探讨多层螺旋CT灌注在非小细胞肺癌放、化疗疗效评定中的作用。方法选择我院收治的48例非小细胞肺癌患者,行多层螺旋CT灌注扫描其放、化疗后病灶,利用CT灌注软件处理图像,测定治疗前后病变的血容量(BV),强化峰值(PEI),对比剂达到峰值耗时(TTP),并比较治疗前后差异[1]。结果非小细胞肺癌患者治疗前后血容量,强化峰值差异有统计学意义(P<0.05),对比值达到峰值耗时差异无统计学意义(P>0.05)。结论多层螺旋CT灌注对非小细胞肺癌放、化疗疗效的判断具有重要价值,值得临床推广。

Objective To discuss the role of multislice CT perfusion in the evaluation of radio-chemotherapy in the treatment of non-small cell lung cancer. Methods 48 patients with non-small cell lung cancer were given MSCT perfusion to scan the nidus after radio-chemotherapy. Blood volume （ BV）, peak enhancement image （ PEI）, and time to peak （TIP） contrast agent were detected and compared before and after the treatment. Results The differences of BV and PEI were statistically significant （ P 〈 0. 05 ）, but the differ- ence of TIP showed no statistical significance （ P 〉 0. 05 ）. Conclusion Multislice CT perfusion has important value to judge the curative effect of radio-chemotherapy in the treatment of non-small cell lung cancer, which is worthy of widely clinical promotion.