河北省任县2668名干部职工血脂异常及并发症调查

Investigation on blood lipid abnormality and complications among 2668 cadres and workers in Renxian County of Hebei Province

目的调查分析河北省任县干部职工血脂异常与并发症发病情况,为制定其预防与控制措施提供依据。方法以河北省任县2 668人在职和离退休干部职工为调查对象,对高血脂、高血压、高血糖、超重与肥胖、颈动脉脂质沉积、脂肪肝、眼睑黄色瘤、脑梗死患病情况和放置冠脉支架情况进行流行病学调查。结果在2 668名被调查者中,男性血脂异常标化患病率高于女性,差异有统计学意义(χ2=16.33,P<0.01)。在男性血脂异常患者中,20～29、30～39岁、40～49岁年龄段血脂异常患病率明显高于女性,差异有统计学意义(χ2=19.89、16.68、11.22,P<0.01)。在50岁以后,男女血脂异常患病率的差异无统计学意义(χ2=1.23、2.36,P>0.05)。在血脂异常患者中,常见的慢性并发症高血压、高血糖、超重与肥胖、颈动脉脂质沉积、脂肪肝、眼睑黄色瘤、脑梗死和放置冠脉支架者明显高于血脂正常者,差异均有统计学意义(χ2=98.69、92.23、92.83、187.57、162.32、67.88、12.65、13.96,P<0.01)。结论该县干部职工血脂异常患病率较高,血脂异常与眼睑黄色瘤、心脑血管疾病以及糖尿病等慢性疾病的患病率有关。

[Objective] To investigate and analyze the prevalence of blood lipid abnormality and complications among cadres and workers in Renxian County of Hebei Province, provide the basis for developing prevention and control measures. [ Methods ] 2 668 in-service or retire cadres and workers in Renxian County of Hebei Province were collected. The prevalence of hyperlipemia, hypertension, hyperglycemia, overweight and obesity, carotid artery lipid deposition, fatty liver, xanthoma palpebrarum, cerebral infarction, and coronary stent placement were investigated with epidemiological methods. [ Results ] Among 2 668 people, the standard- ized prevalence rate of blood lipid abnormality in males was significantly higher than that in females （ χ2 = 16.33 ,P 〈 0.01 ）. The prevalence rates of blood lipid abnormality in 20-29, 30-39 and 40- 49 year-old age group in males were significantly higher than those in females （ χ2 = 19.89, 16.68, 11.22, P 〈 0.01 ）. In over 50 year-old age group, there was no significant difference in prevalence rate of blood lipid abnormality between meals and females （χ2 = 1.23, 2.36,P 〉0.05 ）. The prevalence rates of common complications, including hypertension, hyperglycemia, overweight and obesity, carotid artery lipid deposition, fatty liver, xanthoma palpebrarum, cerebral infarction and coronary stent placement, in people with blood lipid abnormality were higher than those in people with normal blood lipid, and the differences were significant （ χ2 =98.69, 92.23, 92.83, 187.57, 162.32, 67.88, 12.65, 13.96 ,P 〈 0.01）. [ Conclusion] The prevalence rate of blood lipid abnormality among cadres and workers in Renxian County is relatively high, and the blood lipid abnormality is related to the prevalence rate of xanthoma palpebrarum, cardiovascular and cerebrovascular diseases, as well as diabetes mellitus.