鞘内注射不同剂量舒芬太尼联合罗哌卡因分娩镇痛临床疗效观察

Clinical Efficacy of Different Doses Sufentanil Combined with Ropivacaine on Labor Analgesia

目的:比较和分析鞘内注射中高低三种剂量舒芬太尼联合罗哌卡因用于分娩镇痛的临床效果。方法:选取我院于2011年1月至2012年10月收治的120例待产的产妇的临床资料,以不同剂量的舒芬太尼(2.0ug,4.0ug和6.0ug)联合罗哌卡因2.0mg进行镇痛效果和不良反应等分析。结果:B、C组的镇痛起效时间、首剂量持续时间、罗哌卡因的用量等指标均显著优于A组P<0.05;B、C组在以上指标之间比较P>0.05。B组新生儿1min及5min的Apgar评分均高于A组和C组。三组间不良反应的发生率具有一定的剂量依赖性特点。结论:鞘内注射4.0ug舒芬太尼联合罗哌卡因2.0mg的分娩镇痛效果较佳,安全可靠,值得临床推广和应用。

Objective： To explore the clinical efficacy of different doses sufentanil combined with ropivacaine on labor analgesia.Methods： 120 cases were randomized into three groups,including A,B and C with 2.0ug,4.0ug 6.0ug sufentanil combined with ropivacaine 2.0mg,and the analgesic efficacy and adverse reactions of three groups were observed.Results： In group B and group C,the onset of analgesia were faster,the anesthetic duration of first dosage was longer,the total dose of ropivacaine was lower（P0.05）.The rate of obstetric forceps and the rate of caesarean section of patients were low and no statistic differences（P0.05）.Conclusion： The intrathecal injection 4.0ug sufentanil combined with ropivacaine 2.0mg is safe and reliable for labor analgesia,and it is worthy of promotion and application.