联合用药治疗儿童过敏性紫癜临床观察

Clinical Observation on Combination Treatment of Children with Allergic Purpura

目的:探讨复方甘草酸苷联合西咪替丁治疗儿童过敏性紫癜的临床效果。方法:选取我院儿童过敏性紫癜患者60例,随机分为两组。所有患者均采取抗过敏及抗感染处理,观察组在此基础上采用复方甘草酸苷联合西咪替丁进行治疗,观察两组患儿的治愈情况,以及临床症状改善情况。结果:观察组有效率为93.3%,明显高于对照组的66.7%,两组相比,差异具有统计学意义,P<0.05。观察组患者的紫癜相关症状消失的时间明显低于对照组,效果显著,差异具有统计学意义。且观察组治疗过程中无不良反应发生,对照组出现4例肝功能损害,发生率为13.3%,两组相比,差异具有统计学意义。结论:采用复方甘草酸苷与西咪替丁两者联合的方法治疗儿童过敏性紫癜,效果显著,安全性高,不良反应少,值得推广。

Objective： To study compound glycyrrhizin combined cimetidine clinical effects of the treatment of children with allergic purpura.Methods： 60 cases of patients with allergic purpura take the children in our hospital,were randomly divided into two groups.All patients taking anti-allergy and anti-infection treatment,observation group on the basis of compound glycyrrhizin combined cimetidine treatment observed two groups of children cured,and the improvement of clinical symptoms.Results： The valid observation group was 93.3%,significantly higher than 66.7%,compared the two groups,the difference was statistically significant（P0.05）.Purpura related symptoms disappear in the observation group patients was significantly lower than the control group,the effect is significant,the difference was statistically significant.No adverse reactions occurred in and observation group therapy process,the control group,four cases of liver dysfunction,the rate was 13.3% compared to the two groups,a statistically significant difference.Conclusion： Compound glycyrrhizin combined cimetidine treatment of children with allergic purpura,the effect is significant,and adverse reactions.