盐酸羟考酮控释片治疗肝癌介入栓塞术后疼痛的疗效观察

The Efficacy Observation of Oxycontin Interventional Treatment of Liver Cancer of Postoperative Pain

目的:观察肝癌介入栓塞治疗术前和术后口服盐酸羟考酮控释片(奥施康定)疼痛治疗效果及其不良反应,探讨合理可行的介入栓塞治疗镇痛方法。方法:90例肝癌介入栓塞术患者,术前1h口服奥施康定10mg,术后口服奥施康定10mg q12h×3d,观察统计镇痛效果及相关副作用。结果:术后12h疼痛发生率为32.2%,24h为8.9%,术后48h后疼痛发生率稳定在3.3%,其中重度疼痛发生率为0。结论:口服奥施康定可有效控制肝癌介入栓塞治疗术中和术后的疼痛,不良反应轻,服用安全。

Objective：To observe the analgesic effect and adverse effect of oral administration Oxycontin（Oxycodone Hydrochloride Controlled-release Tablets） before and after Transcatheter arterial chemoembolization（TACE） treatment of hepatic carcinoma,discuss the reasonable and feasible pain control method for TACE.Methods：90 patients were given 10mg Oxycontin 1h before the interventional therapy,and after operation 10mg for every 12h for 3 days.The efficacy and side effects were observed and recorded.Results：12 and 24 hours after interventional therapy,the incidences of pain were respectively 32.2% and 8.9%.48h after TACE,the incidences of pain were remained around 3.3%.Among all patients,incidence of severe pain is zero.Conclusion：Oral treatment of Oxycontin can be effective in controlling pain of interventional therapy in hepatic carcinoma,less adverse reactions and take safety.